Dr. Jeff Schorey completed his Ph.D. from the University of Texas Health Science Center at San Antonio followed by post-doctoral studies at the Washington University School of Medicine in St. Louis under Dr. Eric Brown. In this post-doctoral work he published studies on mechanisms of M. avium attachment and invasion of epithelial cells and other non-phagocytic cells as well as work on M. tuberculosis and novel mechanisms by which this pathogen can activate complement. This latter work was published in Science in 1997. D. Schorey then joined the faculty in the Department of Biological Sciences at the University of Notre Dame as an Assistant Professor, and is presently the George B. Craig Jr. Professor of Biological Sciences.
Dr. Schorey’s work at Notre Dame has centered on understanding the dynamics of mycobacteria-host cell interactions with a focus on host signaling pathways activated upon infection and how pathogenic mycobacteria modulate this signaling response. His more recent studies have centered on the role of exosomes in regulating the immune response to an M. tuberculosis infection and their potential use in as biomarkers of active tuberculosis.