Dr. Baumgarth is a Professor of Immunology at the Dept. of Pathology, Microbiology & Immunology and the Center for Comparative Medicine, University of California, Davis. Dr. Baumgarth’s research encompasses studies on the regulation of immune responses to infections and B cell biology. Dr. Baumgarth received her veterinary degree and her PhD from the School of Veterinary Medicine, Hannover, Germany. She then conducted post-doctoral studies in Australia and at Stanford University. In 2000 she set-up her own lab at the University of California, Davis, at the Center for Comparative Medicine. She is the current director of a NIH Training grant at UC Davis for DVMs conducting research towards a PhD and the Chair of Graduate Council at UC Davis, overseeing all graduate education at that university. She is a frequent reviewer for the NIH and a Section Editor for the Journal of Immunology.
Dr. Baumgarth has been continuously funded by the NIH for her studies on the regulation of B cell and B cell subset responses. She is also interested in the regulation and function of natural IgM, a product of innate-like B-1 cells. Dr. Baumgarth’s laboratory investigates these topics using mouse models to two very different pathogens and immune responses: Acute influenza virus infection, an infection that fully resolves and induces highly protective and long-lived B cell-mediated immunity, and B cell responses to Borrelia burgdorferi, a bacterial spirochete and the causative agent of Lyme disease. Her laboratory is investigating how infection-induced inflammatory signals shape B cell response quality to induce long-lasting local and systemic immunity to influenza. Her studies on Borrelia burdorferi infection of mice have shown a profound dysregulation in the T-dependent B cell responses after infection, explaining the establishment of bacterial persistence for the life of the mouse.