British Society for Immunology Congress 2017 | 4 - 7 December, Brighton UK

Anne Puel
Imagine, Institute of Genetic Diseases, France

Anne Puel

Imagine, Institute of Genetic Diseases, France

Professional address:      Laboratory of Human Genetics of Infectious Diseases (HGID), INSERM U1163, University Paris Descartes, Imagine Institute, 24 boulevard du Montparnasse, 75015 Paris, France. Tel: +33 1 2 75 43 19; Fax: +33 1 42 75 42 24, E-mail: anne.puel@inserm.fr

 

Associate Professor (Directeur de Recherche DR2, INSERM) and Adjunct Senior Research Associate

HGID Laboratory, INSERM U1163, Imagine Institute, Paris and Rockefeller University, NYC, USA

Group leader: «Human genetic predisposition to fungal diseases»

2006-2014:             Assistant professor (Chargée de Recherche CR1, INSERM)

HGID Laboratory, INSERM U980, Necker Faculty of Medicine, Paris Descartes University, Paris.

Group leader: «Human genetic predisposition to fungal diseases» and co-leader of the group: «Human genetic predisposition to bacterial diseases »

2002- 2006:             Postdoctoral researcher

GHMI Laboratory, INSERM U980, Necker Faculty of Medicine, Paris Descartes University, Paris. «Human genetic predisposition to bacterial diseases »

2000- 2002:             Postdoctoral researcher

Laboratory of Cellular Immunology, INSERM U543, La Pitié Salpétrière Hospital, Paris. “Cellular and molecular mechanisms regulating quantitative antibody production in Biozzi mice”

1997- 2000:             Post-doctoral fellow

Laboratory of Molecular Immunology, the NIH, Bethesda, Maryland, USA. « Identification of the genetic basis for human TB+NK+ SCID: IL-7RA deficiency »

1992- 1996:              PhD in Immunology

Laboratory of Cellular and Clinical Immunology, INSERM U255, Curie Institute, Paris. “Cellular and molecular mechanisms regulating quantitative antibody production in Biozzi mice”

1991- 1992:              Master 2 in Immunology

Institut Pasteur and University Pierre et Marie Curie, Paris VI, Paris

 

15 Main Relevant Publications (out of 133, (H index 49)                                                                                           

  1. Israel L, Wang Y, ..//.. Casanova JL*, Puel A**. 2017. Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity. Cell 168: 789-800
  2. Della Mina E, Borghesi A, ..//.. Casanova JL*, Puel A**. 2017. Inherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblasts. Proc Natl Acad Sci U S A 114: E514-E523
  3. Lévy R, Okada S, ..//.. Casanova JL*, Puel A**. 2016. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency. Proc Natl Acad Sci U S A 113: E8277-E8285
  4. Toubiana J, Okada S, ..//.. Casanova JL*, Puel A**. 2016. Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype. Blood 127: 3154-64
  5. Okada S*, Markle JG*,..//.. Puel A, Sallusto F*, Bustamante J*, Tangye SG*, Casanova JL. 2015. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations. Science 349: 606-13
  6. Ling Y, Cypowyj S, .//. , Casanova JL*, Puel A**. 2015. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. J Exp Med. 212:619-31
  7. Lanternier F, Mahdaviani SA, ..//.., Casanova JL, Puel A*. 2015. Inherited CARD9 deficiency in otherwise healthy children and adults with Candida species-induced meningoencephalitis, colitis, or both. J Allergy Clin Immunol 135:1558-68.e2
  8. Lanternier F, Barbati E, ..//.., Casanova JL, Puel A*. 2015. Inherited CARD9 deficiency in 2 unrelated patients with invasive Exophiala infection. J Infect Dis 211: 1241-50
  9. Boisson B, Wang C, Pedergnana V, Wu L, Cypowyj S, Rybojad M, Belkadi A, Picard C, Abel L, Fieschi C, Puel A*, Li X*, Casanova JL. 2013. An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis. Immunity 39: 676-86
  10. Lanternier F, Cypowyj S, ..//.. Casanova JL, Puel A*. 2013. Primary immunodeficiencies underlying fungal infections. Curr Opin Pediatr 25: 736-47
  11. Lanternier F, Pathan S,..//., Casanova JL*, Picard C*, Grimbacher B*, Puel A**. 2013. Deep dermatophytosis and inherited CARD9 deficiency. N Engl J Med 369: 1704-14
  12. Puel A**, Cypowyj S*,..//.., Picard C, Casanova JL. 2011. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science 332: 65-8
  13. Liu L*, Okada S*,..//.., Puel A**, Casanova JL*. 2011. Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis. J Exp Med 208: 1635-48
  14. Puel A**, Döffinger R, ..//.. Lilic D, Casanova JL. 2010. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med 207:291-7
  15. von Bernuth H, Picard C, ..//.. Puel A, Casanova JL. 2008. Pyogenic bacterial infections in humans with MyD88 deficiency. Science. 321:691-6

 

Ten main INVITED conferences i2016-2017 (out of > 70)                                                                                             

  1. XLIII Annual Meeting of the SPI 2017, June 14-16, Porto, Portugal
  2. 2017 British Society for Medical Mycology BSMM meeting, March 19-21, Birmingham, UK
  3. 2017 CIS annual meeting, March 23-26, Seattle, USA
  4. 2017 HKS meeting, March 30-April 1, New York City, NY, USA
  5. 9th International Congress of Immunodeficiencies (ICID), April 22-23 2017, Tehran, Iran
  6. 16th International Congress of Immunology, August 21-26 2016, Melbourne, Australia
  7. ATS 2016 International Conference, May 13-18, San Francisco, USA
  8. 26th ECCMID, April 9-12, Amsterdam, The Netherlands
  9. 13th ESPD Congress, May 26-28 Paris, France
  10. FOCIS, June 22-252016, Boston, USA
All Sessions by Anne Puel
Plenary: Learning from immunodeficiencies and novel therapeutics in human disease
Brighton Dome
December 7, 2017
09:30 - 12:30