British Society for Immunology Congress 2017 | 4 - 7 December, Brighton UK

Michael Ehrenstein

University College London, UK

Michael Ehrenstein is Professor of Experimental Rheumatology at University College London (UCL) and Honorary Consultant Rheumatologist at University College London Hospitals (UCLH). Before his appointment in 1999 he was awarded an MRC Clinician Scientist to work at the Laboratory of Molecular Biology in Cambridge undertaking fundamental investigations into the molecular basis of antibody diversity.

The objectives of his research group are focused on autoimmune rheumatic disease (in particular rheumatoid arthritis and systemic lupus erythematosus) to:

  • Use biologic therapy as a molecular scalpel to understand the pathogenesis of autoimmune rheumatic disease both in terms of loss of immune tolerance and ongoing inflammation.
  • Elucidate the immunologic basis for adverse effects to biologic therapies.
  • Identify novel therapeutic targets and to improve existing therapies.
  • Target therapies to patients most likely to benefit through identification of predictors of response.